• Mammalian Fatty Acid Synthase
• References
• Signature
• Slides

References

1. 1)      Maier, T., Leibundgut, M., and Ban, N., 2008. The Crystal Structure of a Mammalian Fatty Acid Synthase. Science 321: 1315-1322.
2. 2)      Ventura, R., et al., 2015. Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression. EBioMedicine 2: 808-824.
3. 3)      Mullen, G. and Yet, L., 2015. Progress in the development of fatty acid synthase inhibitors as anticancer agents. Bioorganic and Medicinal Chemistry Letters 25: 4363-4369.
4. 4)      Protein identification and analysis tools on the ExPASy server. Gasteiger, E. et. al. In J. M. Walker (Ed.) The proteomics protocols handbook. Totowa, New Jersey: Humana Press Inc. 2005.
5. 5)      PSI-BLAST. http://blast.ncbi.nlm.nih.gov/Blast.cgi?CMD=Web&PAGE=Proteins
6. 6)      Holm L, Rosenström P (2010) Dali server: conservation mapping in 3D. Nucl. Acids Res. 38, W545-549.
7. 7)      Pappenberger, G., et al., 2010. Structure of the Human Fatty Acid Synthase KS-MAT Didomain as a Framework for Inhibitor Design. Journal of Molecular Biology 397: 508-519.
8. 8)      Tang, Y., et al., 2006. The 2.7-Å crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerthronolide B synthase. Proceedings of the Natural Academy of Sciences 103: 11124-11129.